Electrical & Computer Engineering

Electrical & Computer Engineering at the University of Delaware

ECE

Upcoming Seminars

November 18, 2009

Hybrid Silicon-based Light-Emitting Platforms

Dr. Sylvain G. Cloutier
Assistant Professor of Electrical and Computer Engineering, University of Delaware

November 18, 2009

The Technical and Political Evolution of the Internet - A Personal Perspective

Dr. David Farber
Distinguished Career Professor of Computer Science and Public Policy at Carnegie Mellon University

February 17, 2010

Information Theory Today

Prof. Sergio Verdu
Eugene Higgins Professor of Electrical Engineering at Princeton University

March 10, 2010

Prospects for Superconducting Quantum Computers

David Divincenzo
Research Staff at the IBM T. J. Watson Research Center in Yorktown Heights, NY

April 14, 2010

US Utility Sector - Turmoil and Transition

James Miller
Chairman, President and chief executive officer of PPL Corporation

Past Seminars

November 18, 2009

Hybrid Silicon-based Light-Emitting Platforms

Dr. Sylvain G. Cloutier
Assistant Professor of Electrical and Computer Engineering, University of Delaware

November 11, 2009

http://www.ece.udel.edu/lectures/DeSalvoo110409.php

Dr. Michael E. Mackay
Department of Materials Science and Engineeing, University of Delaware

September 16, 2009

One View of Nanotechnology

Dr. Robert Opila
Department of Materials Science and Engineering, University of Delaware

June 24, 2009

Light-emitting silicon nitride photonic-plasmonic structures:
a novel materials platform for silicon photonics

Professor Luca Dal Negro
Department of Electrical & Computer Engineering, Boston University

May 20, 2009

Intrusion Detection Systems (IDS) Rises from the Ashes

Tony Pressley
US Army Research Lab

May 18, 2009

Extensions of Compressed Sensing by Exploiting Prior Knowledge

Inaki Esnaola Cano
Department of Electrical and Computer Engineering
University of Delaware

May 13, 2009

Active Photonic Nanomaterials:
From Disordered to Periodic Structures

Hui Cao
Yale University

May 8, 2009

Delineating Molecular Signatures of Disease with Novel Molecular Imaging Probes

Andrew Tsourkas
Department of Bioengineering
University of Pennsylvania

April 29, 2009

Quantum Dot Molecules

Dr. Matt Doty
Materials Science & Engineering, University of Delaware

April 22, 2009

Range Test Validation Cloud Tracking System

James O. Jenson
U.S. Army Edgewood Chemical and Biological Center

April 15, 2009

Polymer-based solar cells - What is the morphology in the device and how does this influence performance?

Dr. Michael Mackay
Materials Science & Engineering, University of Delaware

April 13

Reducing the Complexity of MIMO Detection

Zhiyuan Yan
Department of Electrical and Computer Engineering, Lehigh University

April 10

Fluorescence Imaging of Ventricular Fibrillation and How it May be Caused by Local Ischemia and Reperfusion

Dr. Matthew Kay
Dept. of Electrical and Computer Engineering, George Washington University

April 8

Mid-Infrared Quantum Cascade Lasers

Claire Gmachl
Dept. of Electrical Engineering & MIRTHE, Princeton University

April 6

Filter Design with Secrecy Constraints

Miguel Rodrigues
Instituto de Telecomunicacoes, Department of Computer Science, University of Porto, Portugal

March 25

Functionalized Carbon Nanostructures for Chemical Sensing

Professor A.T. Charlie Johnson
Dept. of Physics and Astronomy, University of Pennsylvania

March 18

THz Radiative Transitions “Under Electrical Breakdown of Shallow
Impurity Centers in Semiconductor Structures”

Dr Alex Andrianov
Ioffe Institute, St. Petersburg, Russia

March 13

Breaking out of silos to solve problems: an example of persistent surveillance

Dr. Neal Gallagher
University of Central Florida

March 13

Tissue Engineering Strategies for Cardiac Repair and Replacement

Dr. Lauren Black
University of Minnesota

March 11

InP-based Quantum Dash Broadband Emitters

Boon Ooi
Center for Optical Technology and Department of Electrical & Computer Engineering
Lehigh University, Pennsylvania

March 9

A Little Bit is a Big Achievenment: Overcoming Barriers in Nano-scale Magnetic Recording

Thomas Clinton
Research Division, Seagate Technology

March 4

Can A Computer Architect Strengthen IT Security?

J. Hirofume Sakane
Japan's National Institute of Advanced Industrial Science and Technology

March 4

Measurements for the Reliability and Electrical Characterization of Nano-Scale Electronics

Curt Richter & John Suehle
Semiconductor Electronics Division, NIST, Gaithersburg, MD

February 25

Using Terahertz Pulses for the Investigation and Control of Charge Dynamics

J. Michael Klopf
Jefferson Lab

February 18

Nanotechnology, Electromagnetics & Photonics Engineering Lecturer Series

Leye Aina
Epitaxial Technologies, LLC

February 12

Advances in Organic Light Emitting Diodes and Lasers

Noel Giebink
University of Michigan

February 11

Outlook for Current PV Technologies and Challenges for Next Generation PV

Dr. Robert Birkmire
University of Delaware

February 6

A Nanostructured Photovoltaic Device - The Intermediate Band Solar Cell

Stephen Bremner
University of Delaware

December 10, 2008

Military Imaging System Performance and NRL Optical Sciences Overview

Dr. Ronald Driggers

December 8, 2008

High resolution biomedical imaging with optics and ultrasound

Dr. Takashi Buma
University of Delaware

December 3, 2008

Image Processing at EM Photonics

Dr. Fernando Ortiz

December 1, 2008

MIMO Feedback Beamforming

Xiantao Sun
University of Delaware, Electrical & Computer Engineering Department

November 26, 2008

Computational Array Imaging

Mark Mirotznik
The Catholic University of America

November 24, 2008

Active Plasmonics for Optical Communication and Photovoltaics

Domenico Pacifici
California Institute of Technology

November 24, 2008

Automotive Cyber-Physical Systems

Professor Rahul Mangharam
University of Pennsylvania, Department of Electrical & Systems Engineering

November 21, 2008

Manipulation of Particles in Microchannels using AC Electrokinetics

Dr. Hongseok (Moses) Noh
Drexel University, Department of Mechanical Engineering & Mechanics

November 19, 2008

Liquid Crystal Nanostructured Composites for Photomasking Applications

Anna Fox
Drexel University

November 19, 2008

The 'Red Brick Wall': Effects of CMOS Device Scaling on Global Wires & Potential Optical Solutions

Rohit Nair
University of Delaware, Electrical & Computer Engineering

November 17, 2008

Innovative Internet Transport Protocols

Professor Paul Amer
University of Delaware, Computer and Information Sciences Department

November 14

Neuron Spike Train Classification and Firing Characteristics of Slowly Adapting Pulmonary Stretch Receptors

Yan Chen
University of Delaware, Electrical & Computer Engineering

November 12, 2008

Terahertz guided surface plasmons

Dr. Daniel Mittleman
Rice University, Electrical & Computer Engineering

November 10, 2008

Increasing Downlink Cellular Throughput with Network MIMO Coordination

Professor Howard Huang
Bell Labs (Alcatel-Lucent)

November 3, 2008

Cooperative Beamforming for High Rate Wireless Communications

Professor Athina Petropulu
Drexel University, Electrical & Computer Engineering

October 20, 2008

SensitivityAnalysis of Biochemical ReactionNetworks: Current Techniques and Future Challenges

Professor John Goutsisas
The Johns Hopkins University

October 13, 2008

Current and Next-Generation Passive Optical Networks

Dr. Pat Iannone
AT&T Labs - Research

October 8, 2008

Silcon Nanophotonics: A Platform for High-Performance On-Chip Optical Interconnects

Dr. William Green
IBM Thomas J. Watson Research Center, Yorktown Heights, NY

October 6, 2008

The World of Quantum Information

Professor Marianna Safronova
Department of Physics and Astronomy, University of Delaware

October 3, 2008

Contrast-Enhanced Subharmonic Imaging
- A New Diagnostic Tool

Flemming Forsberg, Ph.D.
Department of Radiology, Thomas Jefferson University

September 29, 2008

A Game-Theoretic Analysis of Decode-and-Forward User Cooperation

Professor Shalinee Kishore
Lehigh University

September 24, 2008

How Does DARPA Work?

Michael Haney, Professor
Electrical & Computer Engineering, University of Delaware

September 15, 2008

Robust Sampling and Reconstruction Mehtods for Sparse Signals in the Presence of Impulsive Noise

Rafael Carrillo
University of Delaware

September 12, 2008

Investigating Solute Transport and Cell-to-Cell Signaling in bone

Liyun Wang, Ph.D.
Mechanical Engineering, University of Delaware

July 24, 2008

Iterative Compilation by Exploration of Kernel Decomposition

William Jalby, Professor
University of Versailles Saint Quentin

May 19, 2008

Recent Advances in Computation Photography

Jingyi Yu, Assistant Professor

Computer and Information Science Department University of Delaware

May 7, 2008

Gauss' Law: What does it NOT say?

H. Brian Sequeira
Johns Hopkins University, Applied Physics Laboratory

April 30, 2008

Circuits with Light at the Nanoscale

Nader Engheta
H. Nedwill Ramsey Professor, University of Pennsylvania
Department of Electrical and Systems Engineering, Philadelphia, Pennsylvania

April 15, 2008

Vacuum Technology Seminar

Varian Inc. Vacuum Technologies

March 7, 2008

Microfluidic Cell Arrays for High Throughput Signal Pathway Profiling and Drug Screening

Professor Sihong Wang
Department of Biomedical Engineering, City University of New York

February 15,

Flow Control on the Micro-Scale

Dr. Benjamin Shapiro, Associate Professor
University of Maryland, Department of Aerospace Engineering

December 5, 2007

High Power Diode Lasers and Applications

Dr. Wei Gao, President and CTO
Axcel Photonics

November 30, 2007

Fascinating Rhythms:
Reverse Engineering Cortical Function from Changes in Brain Oscillations in Neurological and Psychiatric Disease

Leif Finkel, MD, PhD
University of Pennsylvania, Department of BioEngineering

November 26, 2007

Molecular Level Modeling and Dynamic Analysis of Biochemically Coupled Multicellular Systems

Michael Henson
University of Massachusetts Amherst

November 21, 2007

Nanostructures for Potential Signal Transduction Constructed via Molecular Self-Assembly

Dr. Darrin Pochen
University of Delaware, Materials Science and Engineering

November 19, 2007

Optimal Precoding for Multiple-Input Multiple-Output Gaussian Channels with Arbitrary Inputs

Dr. Fernando Perez-Cruz
Universidad Carlos III & Princeton University (joint work with Miguel Rodrigues and Sergio Verdu)

November 12, 2007

Random Control Bounds for Block Coded Transmission over Fading MIMO
Multiple Access Channel

November 7, 2007

Metal/Semiconductor Nanocomposites

Professor Joshua Zide
University of Delaware

November 2, 2007

Engineering Cancer Therapies: Mathematical Modeling of Tumor Metabolism
and Therapeutic Efficacy

Professor Neil Forbes
University of Massachusetts Amherst

October 31, 2007

Finite Difference Delay

Dr. Xiaobo Wang
University of Delaware

October 19, 2007

Scheduling of Optimal Medication Strategies for Early HIV Infection

Professor Antonios Armaou
Pennsylvania State University

October 17, 2007

Is There Life on the Moon?

Professor Brian Sequeira
Johns Hopkins APL

April 30, 2007

Distributed Processing over Adaptive Networks

Professor Ali H. Sayed
University California, Los Angeles

April 9, 2007

Thoughts on Innovation

Ray Sokola,
Chief Technology Officer Motorola Inc.

Monday, March 12, 2007

Packet Switching Comes of Age: From Research to Commercial Development

Dr. W. David Sincoskie

March 5, 2007

Wireless Sensor Networks

Professor Edward Coyle,
Purdue University

Wednesday February 14, 2007

Confessions of an Internet Timekeeper

Dr. David L. Mills
The University of Delaware, Department of Electrical and Computer Engineering

 

Contrast-Enhanced Subharmonic Imaging

- A New Diagnostic Tool

 

 

Flemming Forsberg, Ph.D.

 
Department of Radiology
Thomas Jefferson University
12:15 AM, Evans Hall, Room 204

Abstract:

The use of gas filled microbubbles (1 to 10 mm in diameter) as vascular tracers and contrast agents for ultrasound imaging is well established by now.  Such contrast agents are used world wide to improve the diagnostic capabilities of ultrasound imaging especially when employed in combination with novel nonlinear contrast imaging modes such pulse inversion second harmonic and subharmonic imaging (SHI).  Our group has investigated the use of SHI in breast imaging and has produced the first ever human SHI images.  Fourteen patients with 16 breast lesions, who underwent breast biopsies with histopathological assessment, participated in a pilot study of mammography and contrast US.  A Logiq 9 scanner (GE Healthcare, Milwaukee, WI) was modified to perform grayscale SHI (transmitting/receiving at 4.4/2.2 MHz).  Of the 16 lesions 4 (25%) were malignant.  Mammography had a sensitivity of 100 % and a specificity of 20 %. Baseline grayscale US and PDI both achieved a sensitivity of 50 % and a specificity of 92 %, while contrast-enhanced PDI produced 75 % and 75 %, respectively.  SHI had a sensitivity of 75 % and specificity of 83 %. All the ultrasound modes produced higher specificities than mammography (p<0.04).  The area under the ROC curve for the detection of breast cancer was highest with SHI (0.78); all though the difference was not statistically significant in this small study population (p>0.20). More recently, the utility of contrast microbubbles for quantitative measurements of perfusion (in ml/min/g) and hydrostatic pressure (in mmHg) have been explored.  Flash-replenishment techniques and subharmonic perfusion estimation have been explored by our group and others and excellent correlations have been reported (r>0.9).  Changes in ambient pressure affect the reflectivity of ultrasound contrast microbubbles leading to an excellent correlation between subharmonic signals and hydrostatic pressure.  We have proposed subharmonic aided pressure estimation (SHAPE; U.S. patent 6,302,845) and provided proof of concept of the feasibility of in vivo SHAPE.  The aortas of two dogs were scanned with a SHAPE transducer assembly.  Simultaneously, the instantaneous pressures within the aorta were measured using a manometer-tipped catheter.  The instantaneous in vivo pressure measurements (from the pressure catheter) and those based on SHAPE were in good accordance over a pressure range of 10 to 60 mmHg with standard errors around 5 mmHg.  In conclusion, a new contrast specific imaging technique, SHI, has been investigated for in vivo breast imaging and for quantitative measurements.  SHI appear to improve the diagnosis of breast cancer relative to conventional ultrasound and mammography; albeit based on a very limited patient population.  Some encouraging results in flow and pressure estimation have been achieved.

Bio: 

Flemming Forsberg was born in Copenhagen, Denmark on October 20, 1961.  He received an M.Sc. in Electronic Engineering and a Ph.D. in Biomedical Engineering from the Technical University of Denmark, Lyngby, Denmark in 1987 and 1990, respectively. From 1987 to 1990 he worked on Doppler ultrasound signal processing at the Electronics Institute, Technical University of Denmark before becoming a post-doctoral research fellow at King’s College, London, England (1990-91).  After a year in private industry, developing an intravascular imaging system, Dr. Forsberg went to the department of Radiology, Thomas Jefferson University, Philadelphia, USA where he is currently a Professor of Radiology.  His research focuses on ultrasound contrast agents and elastography. Dr. Forsberg is a member of the IEEE and a fellow of the AIUM as well as the AIMBE.  He is a member of the Editorial Boards of Ultrasound in Medicine and Biology and Journal of Ultrasound in Medicine.